Indinavir, ritonavir
They are use as a component of HAART (highly active antiretroviral therapy) and never as a mono-therapy because of the fast formation of the resistance to the entire class of drugs.
1) lipodystrophy ( fat deposition on the back and abdomen, but decrease adipose tissue on the extremities); "buffalo hump"
2) hyperglycemia (from increased insulin resistance)
3) inhibition of P-450
There were listed only important side effects for entire class, but every drug from class has its own adverse effect .
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