Monday, March 25, 2013

B-cell and T-cell functions

    B-cell functions:
1) Hyperacute organ rejection is mediated by AB.
2) Allergy - Type I hypersensitivity - Ig E
3) Cytotoxic hypersensitivity - IgG - Type II hypersensitivity
4) Immune complex hypersensitivity - IgG - Type III hypersensitivity

    T-cell functions:
1) CD4 T-cells help B-cells make ABs and produce gamma-interferon, that activates macrophages.
2) CD8 T-cells kill virus-infected cell directly.
3) Delayed cell-mediated hypesensitivity - Type IV hypersensitivity
4) Acute organ rejection 
5) Chronic organ rejection 

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