Free radical injury makes cells damaged via:
--- membrane lipid peroxidation,
-- protein modification,
- DNA breakage.
This damage can be elimanated by:
-----enzymes: catalase, superoxid dismutase, glutation peroxidase
----spontaneous decay
--- antioxidants: A, C, E
Pathologies caused by free radical injury:
--- IRON overload
--acetominophen
--- reperfusion after ANOXIA (after thrombolytic therapy)
--retinopathy of prematurity
-----bronchopulmonary dysplasia
--CCI4 that leads to liver necrosis (fatty changes)
--- membrane lipid peroxidation,
-- protein modification,
- DNA breakage.
This damage can be elimanated by:
-----enzymes: catalase, superoxid dismutase, glutation peroxidase
----spontaneous decay
--- antioxidants: A, C, E
Pathologies caused by free radical injury:
--- IRON overload
--acetominophen
--- reperfusion after ANOXIA (after thrombolytic therapy)
--retinopathy of prematurity
-----bronchopulmonary dysplasia
--CCI4 that leads to liver necrosis (fatty changes)
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